Motif ID: TLX1..3_NFIC{dimer}.p2

Z-value: 1.122


Transcription factors associated with TLX1..3_NFIC{dimer}.p2:

Gene SymbolEntrez IDGene Name
TLX1 3195 T-cell leukemia homeobox 1
TLX3 30012 T-cell leukemia homeobox 3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
TLX3chr5_+_1707362870.442.9e-02Click!
TLX1chr10_+_1028910600.154.7e-01Click!


Activity profile for motif TLX1..3_NFIC{dimer}.p2.

activity profile for motif TLX1..3_NFIC{dimer}.p2


Sorted Z-values histogram for motif TLX1..3_NFIC{dimer}.p2

Sorted Z-values for motif TLX1..3_NFIC{dimer}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TLX1..3_NFIC{dimer}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_79086087 6.772 NM_006820
IFI44L
interferon-induced protein 44-like
chr16_+_57406398 4.931 NM_002996
CX3CL1
chemokine (C-X3-C motif) ligand 1
chr15_+_89182038 4.137 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr6_-_31550065 4.028 NM_002341
NM_009588
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr1_-_173020011 3.546 NM_005092
TNFSF18
tumor necrosis factor (ligand) superfamily, member 18
chr17_+_77030471 3.125 NM_198593
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr6_+_14117857 3.008 NM_001040280
NM_004233
CD83

CD83 molecule

chr2_-_7005764 2.810 NM_207315
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr8_-_80679897 2.793 NM_001040708
NM_012258
HEY1

hairy/enhancer-of-split related with YRPW motif 1

chr6_+_14117486 2.746 NM_001251901
CD83
CD83 molecule
chr1_-_173174611 2.153 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr19_+_10397642 2.077 NM_001039132
NM_001544
NM_022377
ICAM4


intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)


chr1_+_79115476 2.074 NM_006417
IFI44
interferon-induced protein 44
chr15_-_72523557 1.940 PKM2
pyruvate kinase, muscle
chr17_+_40439564 1.934 NM_003152
STAT5A
signal transducer and activator of transcription 5A
chr15_-_72523542 1.932 PKM2
pyruvate kinase, muscle
chr15_-_72523483 1.913 PKM2
pyruvate kinase, muscle
chr15_-_72523713 1.889 NM_001206796
NM_001206797
NM_001206798
NM_002654
NM_182470
NM_182471
PKM2





pyruvate kinase, muscle





chr12_+_124773709 1.885 NM_181709
FAM101A
family with sequence similarity 101, member A
chr6_-_43595046 1.858 GTPBP2
GTP binding protein 2

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
2.00 3.05e-02 GO:0005578 proteinaceous extracellular matrix
1.90 3.82e-02 GO:0031012 extracellular matrix
1.66 4.78e-04 GO:0044421 extracellular region part
1.62 1.34e-04 GO:0031226 intrinsic to plasma membrane
1.62 1.77e-04 GO:0005887 integral to plasma membrane
1.58 3.82e-02 GO:0005626 insoluble fraction
1.50 3.46e-02 GO:0000267 cell fraction
1.45 1.12e-04 GO:0044459 plasma membrane part
1.39 5.47e-03 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.55 2.29e-02 GO:0005102 receptor binding